2013 – Biobran https://biobran.org Sun, 23 Aug 2026 14:13:04 +0000 en-US hourly 1 https://wordpress.org/?v=7.1 https://biobran.org/wp-content/uploads/2026/08/cropped-FaviBB-1-32x32.webp 2013 – Biobran https://biobran.org 32 32 Case Reports of Cancer Patients with Hepatic Metastases Treated by Standardized Plant Immunomodulatory Preparations https://biobran.org/case-reports-of-cancer-patients-with-hepatic-metastases-treated-by-standardized-plant-immunomodulatory-preparations/ Fri, 16 Aug 2013 18:02:00 +0000 https://biobran.org/?p=701 Background: Metastatic hepatocellular carcinoma often has a multifocal tumor pattern with markedly depressed hepatic function, Hepatic resection in many cases results in no long-term benefit. After a chemotherapy hepatic tumors rarely disappear completely and the duration of responses is short, ln the last decades growing evidence suggested that a disturbed balance in the innate system can also play a role in the poor prognosis of hepatic tumors.
Objectives: The aim of this article is to present and discuss several favorable clinical responses of patients with hepatic metastases who parallel to conventional oncologic therapy, were treated with immunologically effective and standardized plant extracts.
Course of Therapy and Results: In accordance with the bell-shaped dose-response relationship of mistletoe Iectins (MLs), the patients were treated with a fermented mistletoe extract (ME) preparation, standardized for the active sugar-binding lectin contents, Thus, an optimal dose between 0.5 and 1,0ng/kg MLs was given twice a week subcutaneously. In addition to ML therapy, a heteropolysaccharide rice bran preparation standardized for arabinoxylan (12-45mg/kg MGN-3/Biobran twice a week) and wheat germ extract (WGE) standardized for 2, 6-dimethoxy-p-benzoquinone (50-80mg/kg AvemarR four times a week) was also given. In these case reports the clinical progress of seven patients showed a complete or nearly complete remission of hepatic metastases.
Conclusion: ML, MGN-3 and WGE seem to be potent candidates to be regarded as a supportive therapy to surgery, hormone treatment or chemotherapy for patients with hepatic metastases. These case reports require further clinical studies.

]]> Biobran MGN-3: Effect of reducing side effects of chemotherapy in breast cancer patients https://biobran.org/biobran-mgn-3-effect-of-reducing-side-effects-of-chemotherapy-in-breast-cancer-patients/ https://biobran.org/biobran-mgn-3-effect-of-reducing-side-effects-of-chemotherapy-in-breast-cancer-patients/#respond Fri, 16 Aug 2013 17:58:00 +0000 https://biobran.org/?p=699 Objective: The aim of study was to assess the effect of Biobran in reducing of chemotherapy induced side effects in terms of tiredness, anorexia, vomiting and hair loss and quality of life in terms of weight loss.

Setting: Radiotherapy Department, Nishtar Hospital  Multan.

Material and Methods: Fifty patients of breast cancer were enrolled randomly in two groups. Group—A patients were given 3 gram dose of Biobran MGN-3 per day one week before and one week after chemotherapy. Group-B patient were given chemotherapy alone. Total six cycles of chemotherapy were given. No multivitamin orfood supplements were given during this study.

Chemotherapy induced side effects (tiredness, anorexia, and vomiting, hair loss) were assessed by questionnaire to the patients before start of each cycle. Weight was checked before each cycle to assess weight gain or loss. White blood cells were checked by complete blood count just before and one week after chemotherapy.

Results: Between six months, 50 patients were enrolled in Radiotherapy Department, Nishtar Hospital Multan. There was asignificant reduction in tiredness and anorexia in group—A patients. 20 (80%) patients of group-A felt increase intheirdiet and notiredness without any appetizeror multivitamin. But group—B patients demanded for appetizer due to severe anorexia after chemotherapy except 3 (12%) patients who didn‘t use any appetizer or food supplement. In group-A, 15 (60%) patients didnt need any anti-emetic as compared to group-B all patient (100%) experienced severe nausea during and after chemotherapy. Group—A patients experienced less hairfall 7 (28%) patients as compared to other group which is 25 (100%) patients.

Conclusions: The study showed that, by helping to optimize the immune system, Biobran MGN-3 can not only help maximize treatment success, but also minimize treatment side effects and improve quality of life during treatment and in recovery.

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