Rice bran arabinoxylan compound and quality of life of cancer patients (RBAC – QoL): Study protocol for a randomized pilot feasibility trial
Introduction : Rice bran arabinoxylan com pound (RBAC) is a nutraceutical for enhancing a depleted immune system during and after cancer treatment. This pilot feasibility trial aims to evaluate the effects of RBAC on cancer patients’ quality of life during active treatment, compared to placebo, using a validated questionnaire. Other outcome measures include changes in […]
The Immunomodulating Effects of Arabinoxylan Rice Bran (Lentin) on Hematologic Profile, Nutritional Status and Quality of Life among Head and Neck Carcinoma Patients Undergoing Radiation Therapy: A Double Blind Randomized Control Trial
Immunostimulants have been explored to reduce the complications of radiation/chemotherapy. This double blind randomized trial aimed to determine the immunomodulating effects of Lentin among head and neck cancer patients in addressing radiation treatment complications such as anemia, leukopenia, weight loss and improvement of quality of life. Sixty-five (65) patients were enrolled and given either Lentin […]
Arabinoxylan rice bran (MGN-3/Biobran) alleviates radiation-induced intestinal barrier dysfunction of mice in a mitochondrion-dependent manner
MGN-3 is an arabinoxylan from rice bran that has been shown to be an excellent antioxidant and radioprotector. This study examined the protective effects of MGN-3 on radiation-induced intestinal injury. Mice were treated with MGN-3 prior to irradiation, then continued to receive MGN-3 for 4 weeks thereafter. MGN-3 increased the activity of mitochondrial respiratory chain […]
Chemopreventive role of arabinoxylan rice bran, MGN-3/Biobran, on liver carcinogenesis in rats
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world and one of the most lethal. MGN-3/Biobran is a natural product derived from rice bran hemicelluloses and has been reported to possess a potent anticancer effect in a clinical study of patients with HCC. The current study examines the mechanisms by which […]