Effect of Long-term Administration of Immunomodulatory Food on Cancer Patients Cmpleting Conventional Treatments
A study was conducted to investigate the effects of long—term administration of the immunomodulatory food modified arabinoxylan from rice bran (BioBran/MGN-3), on 16 cancer patients, mainly in stage IV with various conventional lesions, who had just undergone conventional cancer treatments, such as surgery, chemotherapy and radiotherapy. The main clinical observations were the safety and effect of BioBran […]
Home Products Research Distributors Contact Enhancement of natural killer cell activity of aged mice by modified arabinoxylan rice bran (MGN-3/Biobran).
The present study is aimed to examine the possibility of enhancement of natural killer (NK) cell activity in aged C57BL/6 and C3H mice using MGN-3, a modified arabinoxylan from rice bran. Intraperitoneal injection of MGN-3 (10 mg kg(-1) per day) caused a remarkable increase in the peritoneal NK activity as early as 2 days (35.2 […]
Home Products Research Distributors Contact Experience with Administration of BioBran in Patients with Chronic Rheumatism
The functional food, rice bran arabynoxylan derivative (BioBran), was administered for a long period to patients with chronic rheumatism given mainly symptomatic treatments with steroids, to evaluate its supplementary effect with representative treatments for rheumatism, such as steroids, analgesics, and thermotherapy. Steroids are essential for treatment of rheumatism, but it is desirable to minimize the […]
One Case of a Patient with Umbilical Metastasis of Recurrent Cancer (Sister Mary Joseph’s Nodule, SMJN) Who has Survived for a Long Time under Immunomodulatory Supplement Therapy
A 64-year-old female patient with umbilical metastasis of recurrent colorectal cancer (SMJN) was subjected to complementary medicine using the rice bran arabinoxylan derivative, a food component of BRM activity in addition to chemotherapy in order to maintain the QOL and prolong life. Although the umbilical metastasis is tending to grow, the patient is in a […]
Oral administration of hydrolyzed rice bran prevents the common cold syndrome in the elderly based on its immunomodulatory action
The preventive effect of Hydrolyzed Rice Bran against the common cold syndrome was examined in elderly people. Arabinoxylan derivatives of Hydrolyzed Rice Bran (HRB) were prepared from water-soluble rice bran through partial processing using a carbohydrate complex. Using the water-soluble Rice Bran (RB) as a control, a cross over double-blind study was conducted on both […]
The Clinical Significance of BioBran in the Immunotherapy for Cancer
The clinical treatments for cancer were surgery, radiotherapy, and chemotherapy with anticancer drugs. For surgery, even if the procedure used is highly sophisticated, cancer cells may be transported to other organs via the vascular or lymph system. For radiotherapy, although it destroys cancer tissues it may also damage the surrounding functioning tissues. Anticancer drugs may […]
The Life Prolongation and QOL Improvement Effect of Rice Bran Arabinoxylan Derivative (MGN-3, BioBran) for Progressive Cancer
The present study was designed to deremine whether or not the administration of MGN-3 coud have its apothanasia effect and improve the QOL for 205 progressive and partially metastasized cancer patients in late III-IV stages after surgery. MGN-3 is a rice bran arabinoxylan derivative and known to have immunomodulation activity. The participants in this clinical […]
The orally administration of the Hydrolysis Rice Bran prevents a common cold syndrome for the elderly people based on immunomodulatory function
The preventive effect of RIBEX against the common cold syndrome was examined on elderly people. RIBEX, containing arabinoxylan derivatives Hydrolysis Rice Bran (HRB), was prepared from the water soluble dietary fiber fraction from rice bran through partial processing by carbohydrate complex of Lentinus Edodes mycelia (shiitake). Using the non-chemical and non-biological treated water soluble fraction […]
Modified Rice Bran Beneficial for Weight Loss of Mice as a Major and Acute Adverse Effect of Cisplatin
Alkylating agents and antimetabolites remain prominent in a wide variety of cancer chemotherapy protocols on the basis of more selective effects on the faster than normal mitotic cycles of malignant cells. Among new platinum‐containing anticancer molecules, the lead compound cisplatin (Cis‐platinum (II) diammine dichloride) has been known to possess beneficial anticancer properties in terms of […]
Modified arabinoxylan rice bran (MGN-3/Biobran) sensitizes human T cell leukemia cells to death receptor (CD95)-inducted apoptosis
MGN-3, an arabinoxylan extracted from rice bran that is treated enzymatically with an extract from Shiitaki mushrooms, is an effective biological response modifier that increases NK cell activity, and potentiates the activity of conventional chemotherapeutic agents. In this study, we investigated the effect of MGN-3 on death receptor-induced apoptosis in the human leukemic HUT 78 […]