One Case of a Patient with Umbilical Metastasis of Recurrent Cancer (Sister Mary Joseph’s Nodule, SMJN) Who has Survived for a Long Time under Immunomodulatory Supplement Therapy
A 64-year-old female patient with umbilical metastasis of recurrent colorectal cancer (SMJN) was subjected to complementary medicine using the rice bran arabinoxylan derivative, a food component of BRM activity in addition to chemotherapy in order to maintain the QOL and prolong life. Although the umbilical metastasis is tending to grow, the patient is in a […]
Oral administration of hydrolyzed rice bran prevents the common cold syndrome in the elderly based on its immunomodulatory action
The preventive effect of Hydrolyzed Rice Bran against the common cold syndrome was examined in elderly people. Arabinoxylan derivatives of Hydrolyzed Rice Bran (HRB) were prepared from water-soluble rice bran through partial processing using a carbohydrate complex. Using the water-soluble Rice Bran (RB) as a control, a cross over double-blind study was conducted on both […]
The Clinical Significance of BioBran in the Immunotherapy for Cancer
The clinical treatments for cancer were surgery, radiotherapy, and chemotherapy with anticancer drugs. For surgery, even if the procedure used is highly sophisticated, cancer cells may be transported to other organs via the vascular or lymph system. For radiotherapy, although it destroys cancer tissues it may also damage the surrounding functioning tissues. Anticancer drugs may […]
The Life Prolongation and QOL Improvement Effect of Rice Bran Arabinoxylan Derivative (MGN-3, BioBran) for Progressive Cancer
The present study was designed to deremine whether or not the administration of MGN-3 coud have its apothanasia effect and improve the QOL for 205 progressive and partially metastasized cancer patients in late III-IV stages after surgery. MGN-3 is a rice bran arabinoxylan derivative and known to have immunomodulation activity. The participants in this clinical […]
The orally administration of the Hydrolysis Rice Bran prevents a common cold syndrome for the elderly people based on immunomodulatory function
The preventive effect of RIBEX against the common cold syndrome was examined on elderly people. RIBEX, containing arabinoxylan derivatives Hydrolysis Rice Bran (HRB), was prepared from the water soluble dietary fiber fraction from rice bran through partial processing by carbohydrate complex of Lentinus Edodes mycelia (shiitake). Using the non-chemical and non-biological treated water soluble fraction […]
Modified Rice Bran Beneficial for Weight Loss of Mice as a Major and Acute Adverse Effect of Cisplatin
Alkylating agents and antimetabolites remain prominent in a wide variety of cancer chemotherapy protocols on the basis of more selective effects on the faster than normal mitotic cycles of malignant cells. Among new platinum‐containing anticancer molecules, the lead compound cisplatin (Cis‐platinum (II) diammine dichloride) has been known to possess beneficial anticancer properties in terms of […]
Modified arabinoxylan rice bran (MGN-3/Biobran) sensitizes human T cell leukemia cells to death receptor (CD95)-inducted apoptosis
MGN-3, an arabinoxylan extracted from rice bran that is treated enzymatically with an extract from Shiitaki mushrooms, is an effective biological response modifier that increases NK cell activity, and potentiates the activity of conventional chemotherapeutic agents. In this study, we investigated the effect of MGN-3 on death receptor-induced apoptosis in the human leukemic HUT 78 […]
MODIFIED RICE BRAN, MGN-3, IMPROVES GLUCOSE TORELANCE IN NIDDM ADULT RATS GIVEN STREPTOZOTOCIN AS NEONATES
The effect of modified rice bran (MGN-3) on glucose tolerance as studied in NIDDM adult rats and changes in taste preference were also examined. NIDDM adult rats were made by intraperitoneal injection of 100mg streptozotocin at 1.5 days of age. Following weaning, the animals were divided into 3 groups, control, diabetic rats fed 1% cellulose […]
The basic study of arabinoxylan compound (MGN-3) on the activation of vital defence
Arabinoxylan (hereafter called MGN-3) is a plant polysaccharide processed food with a biophylactic action, which mainly contains polysaccharides such as hemicellulose and arabinoxylan and glycoprotein. MGN-3 is known to have various biophylactic actions such as in vitro NK cell activity stimulation and anti-HIV effect. In the present study, the vital defense activating effect of MGN-3 […]
The Effect of MGN-3 on Cisplatin and Doxorubicin Induced Toxicity in the Rat
MGN-3 BioBran is derived from rice bran and is produced by the partial hydrolysis of the water soluble hemicellulose fraction of rice bran by carbohydrases derived from Lentius edodes mycelia. It is a biological response modifier producing an increase in natural killer cell activity in immunocompromised patient. The aim of the study was to evaluate orally […]